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ASTM F750-87(2002)e1

Historical Reaffirmation

Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

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1.1 This practice covers a nonspecific, acute toxicity test used for detecting leachables from materials used in medical devices.

1.2 The liquids injected in the mouse are those obtained by Practice F 619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.

1.3 Two procedures are outlined: Method A for intravenous injection and Method B for intraperitoneal injection.

1.4 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F 748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.


SDO ASTM: ASTM International
Document Number F750
Publication Date Sept. 25, 1987
Language en - English
Page Count 3
Revision Level 87(2002)e1
Supercedes
Committee F04.16
Publish Date Document Id Type View
June 1, 2020 F0750-20 Revision
Feb. 1, 2007 F0750-87R07E01 Revision
Oct. 1, 2012 F0750-87R12 Reaffirmation
Feb. 1, 2007 F0750-87R07 Reaffirmation
Sept. 25, 1987 F0750-87R02E01 Reaffirmation
Sept. 25, 1987 F0750-87R02 Reaffirmation
Sept. 25, 1987 F0750-87R96 Reaffirmation