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ASTM F749-98(2002)e1

Historical Reaffirmation

Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit

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1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices.

1.2 The liquids injected in the rabbits are those obtained by Practice F 619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.

1.3 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F 748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.

1.4 The values stated in SI units are to be regarded as the standard.


SDO ASTM: ASTM International
Document Number F749
Publication Date Feb. 10, 1998
Language en - English
Page Count 2
Revision Level 98(2002)e1
Supercedes
Committee F04.16
Publish Date Document Id Type View
Feb. 1, 2020 F0749-20 Revision
March 1, 2013 F0749-13 Revision
Feb. 1, 2007 F0749-98R07E01 Revision
Feb. 10, 1998 F0749-98R02E02 Revision
Feb. 10, 1998 F0749-98 Revision
Oct. 1, 2012 F0749-98R12 Reaffirmation
Feb. 1, 2007 F0749-98R07 Reaffirmation
Feb. 10, 1998 F0749-98R02E01 Reaffirmation