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ASTM E1601-19

Current Revision

Standard Practice for Conducting an Interlaboratory Study to Evaluate the Performance of an Analytical Method

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1.1 This practice covers procedures and statistics for an interlaboratory study (ILS) of the performance of an analytical method. The study provides statistical values which are useful in determining if a method is satisfactory for the purposes for which it was developed. These statistical values may be incorporated in the method's precision and bias section. This practice discusses the meaning of the statistics and what users of analytical methods may learn from them.

1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.

1.3 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.


5.1 Ideally, interlaboratory testing of a method is conducted by a randomly chosen group of laboratories that typifies the kind of laboratory that is likely to use the method. In actuality, this ideal is only approximated by the laboratories that are available and willing to undertake the test work. The coordinator of the program must ensure that every participating laboratory has appropriate facilities and personnel and performs the method exactly as written. If this goal is achieved, the statistics developed during the ILS will be adequate for determining if the method is capable of producing satisfactory precision in actual use. If the program includes certified reference materials, the test data also provide information concerning the bias of the method. The statistics provide a general guide to the expected performance of the method.

SDO ASTM: ASTM International
Document Number E1601
Publication Date Nov. 1, 2019
Language en - English
Page Count 14
Revision Level 19
Supercedes
Committee E01.22
Publish Date Document Id Type View
Nov. 1, 2019 E1601-19 Revision
Dec. 15, 2012 E1601-12 Revision
May 15, 2010 E1601-10 Revision
May 10, 1998 E1601-98 Revision
Oct. 1, 2003 E1601-98R03E01 Reaffirmation